Single Embryo Transfer Versus Double Embryo Transfer: A Cost-Effectiveness Analysis in a Non-IVF Insurance Mandated System

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Economic evaluations of single- versus double-embryo transfer in IVF.

Multiple pregnancies lead to complications and induce high costs. The most successful way to decrease multiple pregnancies in IVF is to transfer only one embryo, which might reduce the efficacy of treatment. The objective of this review is to determine which embryo-transfer policy is most cost-effective: elective single-embryo transfer (eSET) or double-embryo transfer (DET). Several databases w...

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Single versus double embryo transfer: cost-effectiveness analysis alongside a randomized clinical trial.

BACKGROUND Twin pregnancies after IVF are still frequent and are considered high-risk pregnancies leading to high costs. Transferring one embryo can reduce the twin pregnancy rate. We compared cost-effectiveness of one fresh cycle elective single embryo transfer (eSET) versus one fresh cycle double embryo transfer (DET) in an unselected patient population. METHODS Patients starting their firs...

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Randomized single versus double embryo transfer: obstetric and paediatric outcome and a cost-effectiveness analysis.

BACKGROUND Transfer of several embryos after IVF results in a high multiple birth rate associated with increased morbidity and high costs for the neonatal care. In a previous randomized trial we demonstrated that a single embryo transfer (SET) strategy, including one fresh single embryo transfer and, if no live birth, one additional frozen-thawed SET, resulted in a live-birth rate that was not ...

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Elective single-embryo transfer versus double-embryo transfer in in vitro fertilization.

BACKGROUND The risks of premature birth and perinatal death are increased after in vitro fertilization. These risks are mainly due to the high incidence of multiple births, which relates to the number of embryos transferred. METHODS We performed a randomized, multicenter trial to assess the equivalence of two approaches to in vitro fertilization with respect to the rates of pregnancy that res...

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IVF has been described as one the medical breakthroughs of the 20 th Century. Over 5 million children have been born using the methods first developed by Robert Edwards who died last year. However there is continuing concern about some of the outcomes of IVF treatment (Kamphuis et al., 2014), particularly the high number of multiple births, a problem which became apparent only a few years after...

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ژورنال

عنوان ژورنال: Military Medicine

سال: 2020

ISSN: 0026-4075,1930-613X

DOI: 10.1093/milmed/usaa119